Al-Azhar Assiut Medical Journal

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 14  |  Issue : 2  |  Page : 76--80

Vitamin D deficiency and its correlation to hemoglobin A1C in adolescent and young adult type 1 diabetes mellitus patients


Amira M Elsayed1, Ghada A Mohamed2 
1 Department of Internal Medicine, Benha Faculty of Medicine, Benha University, Benha, Egypt
2 Department of Internal Medicine, Assiut Faculty of Medicine, Assiut University, Assiut, Egypt

Correspondence Address:
Ghada A Mohamed
Department of Internal Medicine, Assiut Faculty of Medicine, Assiut University, PO Box: 71511
Egypt

Background Some studies have described the relationship between autoimmune diabetes or type 1 diabetes mellitus (T1DM) and vitamin D deficiency. Few studies correlate between vitamin D deficiency and glycemic control. Purpose This study was conducted to appraise the status of vitamin D in adolescent and young adult T1DM patients and to correlate its deficiency to glycated hemoglobin (HbA1c). Patients and methods Around 63 Kuwaiti patients with T1DM were recruited in a descriptive cross-sectional study in April 2015. Serum level of vitamin D [25(OH)D] was measured using enzyme-linked immunosorbent assay, and glycemic control was measured by HbA1c using autoanalyzer. The relationship between vitamin D levels and HbA1c was analyzed by Spearman’s correlation. Among the participants, 21 (33.3%) were male and 42 (66.7%) were female. The mean age was 18.41±6.19, and the mean diabetes duration was 6.98±4.99. The mean vitamin D concentration was 47.29±2.91 nmol/l, with 38.1% of participants identified to have vitamin D deficiency and 19% identified to have vitamin D insufficiency. There were high levels of HbA1c (10.08±2.28), with a significant inverse correlation between HbA1c and vitamin D (r=−0.374 and P=0.003). Conclusion Low vitamin D in T1DM is extremely highly and closely correlated to HbA1c. We recommend that evaluation of the level of vitamin D in type 1 diabetic patients is very critical, and vitamin D supplementation may improve glycemic control.


How to cite this article:
Elsayed AM, Mohamed GA. Vitamin D deficiency and its correlation to hemoglobin A1C in adolescent and young adult type 1 diabetes mellitus patients.Al-Azhar Assiut Med J 2016;14:76-80


How to cite this URL:
Elsayed AM, Mohamed GA. Vitamin D deficiency and its correlation to hemoglobin A1C in adolescent and young adult type 1 diabetes mellitus patients. Al-Azhar Assiut Med J [serial online] 2016 [cited 2019 Sep 23 ];14:76-80
Available from: http://www.azmj.eg.net/article.asp?issn=1687-1693;year=2016;volume=14;issue=2;spage=76;epage=80;aulast=Elsayed;type=0