Year : 2016 | Volume
: 14 | Issue : 2 | Page : 76--80
Vitamin D deficiency and its correlation to hemoglobin A1C in adolescent and young adult type 1 diabetes mellitus patients
Amira M Elsayed1, Ghada A Mohamed2
1 Department of Internal Medicine, Benha Faculty of Medicine, Benha University, Benha, Egypt
2 Department of Internal Medicine, Assiut Faculty of Medicine, Assiut University, Assiut, Egypt
Some studies have described the relationship between autoimmune diabetes or type 1 diabetes mellitus (T1DM) and vitamin D deficiency. Few studies correlate between vitamin D deficiency and glycemic control.
This study was conducted to appraise the status of vitamin D in adolescent and young adult T1DM patients and to correlate its deficiency to glycated hemoglobin (HbA1c).
Patients and methods
Around 63 Kuwaiti patients with T1DM were recruited in a descriptive cross-sectional study in April 2015. Serum level of vitamin D [25(OH)D] was measured using enzyme-linked immunosorbent assay, and glycemic control was measured by HbA1c using autoanalyzer. The relationship between vitamin D levels and HbA1c was analyzed by Spearman’s correlation. Among the participants, 21 (33.3%) were male and 42 (66.7%) were female. The mean age was 18.41±6.19, and the mean diabetes duration was 6.98±4.99. The mean vitamin D concentration was 47.29±2.91 nmol/l, with 38.1% of participants identified to have vitamin D deficiency and 19% identified to have vitamin D insufficiency. There were high levels of HbA1c (10.08±2.28), with a significant inverse correlation between HbA1c and vitamin D (r=−0.374 and P=0.003).
Low vitamin D in T1DM is extremely highly and closely correlated to HbA1c. We recommend that evaluation of the level of vitamin D in type 1 diabetic patients is very critical, and vitamin D supplementation may improve glycemic control.
Ghada A Mohamed
Department of Internal Medicine, Assiut Faculty of Medicine, Assiut University, PO Box: 71511
|How to cite this article:|
Elsayed AM, Mohamed GA. Vitamin D deficiency and its correlation to hemoglobin A1C in adolescent and young adult type 1 diabetes mellitus patients.Al-Azhar Assiut Med J 2016;14:76-80
|How to cite this URL:|
Elsayed AM, Mohamed GA. Vitamin D deficiency and its correlation to hemoglobin A1C in adolescent and young adult type 1 diabetes mellitus patients. Al-Azhar Assiut Med J [serial online] 2016 [cited 2020 Jul 13 ];14:76-80
Available from: http://www.azmj.eg.net/article.asp?issn=1687-1693;year=2016;volume=14;issue=2;spage=76;epage=80;aulast=Elsayed;type=0