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ORIGINAL ARTICLE
Year : 2019  |  Volume : 17  |  Issue : 4  |  Page : 393-397

Prevalence and risk factors of pregabalin misuse among patients with substance use disorder


Department of Psychiatry, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Correspondence Address:
Amgad A.M Gabr
Al Mokhaym Al Daem, Gameat Al-Azhar, Nasr City, Cairo Governorate, Cairo 11751, Egypt; Al Mokhaym Al Daem, Al Azhar Unversity, Nasr City Cairo, Egypt. Post Office No.11751
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/AZMJ.AZMJ_126_19

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Background Pregabalin use disorder is an alarming phenomenon demonstrated in many countries. Some countries classified it as a class C controlled substance in a schedule V controlled substance. Aim The aim was to assess pregabalin use disorder among substance abusers, recognize psychiatric co-morbidity, and identify risk factors to start pregabalin abuse. Participants and methods The study group included 400 Egyptian substance misusers. From addiction and psychiatric outpatient clinics in Al-Azhar University Hospitals in Cairo, Egypt, the participants were diagnosed using DSM V and interviewed using (SCID 1) and urine specimens screened for routine polysubstance and pregabalin by means of a mass spectrometer analysis. Results The prevalence of pregabalin misuse disorder among all patients with substance misuse disorder was 30%. However, first substance is cannabinoids (hashish), with 83.75%, and then tramadol, with 43.75%. The prevalence of co-morbid psychiatric disorders was 45%. We found the use of pregabalin for sleep purpose 32.5% and for anxiety self-treatment 19.2% as the strongest predictors and risk factors for pregabalin abuse. Conclusion Pregabalin misuse disorder is at the fourth rank among all substances misused in Egypt, with a percentage of 30%. The most common reason for pregabalin misuse is to have a good sleep, self-treatment of anxiety, peer pressure, and depression.


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