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Year : 2019  |  Volume : 17  |  Issue : 3  |  Page : 319

Seroprevalence of leptospirosis among people in Shabramant Village, Egypt

Paediatrics and Child Health, Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Submission09-Mar-2019
Date of Decision27-Mar-2019
Date of Acceptance17-Jun-2019
Date of Web Publication26-Nov-2019

Correspondence Address:
Mahmood D Al-Mendalawi
PO Box 55302, Baghdad Post Office, Baghdad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/AZMJ.AZMJ_45_19

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How to cite this article:
Al-Mendalawi MD. Seroprevalence of leptospirosis among people in Shabramant Village, Egypt. Al-Azhar Assiut Med J 2019;17:319

How to cite this URL:
Al-Mendalawi MD. Seroprevalence of leptospirosis among people in Shabramant Village, Egypt. Al-Azhar Assiut Med J [serial online] 2019 [cited 2020 Jul 6];17:319. Available from: http://www.azmj.eg.net/text.asp?2019/17/3/319/271678

I read with great interest the study by Elzahaby et al. [1] published in the April to June 2018 issue of the Al-Azhar Assiut Medical Journal. On employing microagglutination test (MAT), the authors found leptospirosis to be common among the studied cohort (44%) [1]. I assume that such finding ought to be taken cautiously. This is based on the presence of the following methodological limitations related to the tool employed to diagnose leptospirosis. It is explicit that MAT takes several days before the results become positive after the onset of illness. Moreover, MAT requires skilled handling and also needs the maintenance of live Leptospira cells representing all serogroups [2]. Currently, real-time PCR testing of LipL32 antigen provides the earliest detection of pathogenic Leptospira in the body with 100% specificity [3]. I assume that if Elzahaby et al. [1] employed PCR in the methodology instead of MAT, more accurate results might be obtained. Despite that limitation, the worryingly high reported leptospirosis prevalence (44%), which is nearly comparable to 49.7% previously reported by Samir et al. [4], necessitates implementation of strict public health measure to counteract this serious zoonotic infection in Egypt.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Elzahaby AA, Zaky S, Hafez Hassanain NA, Hassan ESR, Hafez Hassanain MA, Hegazy M et al. Seroprevalence of leptospirosis among people in Shabramant Village, Egypt. Al-Azhar Assiut Med J 2018; 16:168–175.  Back to cited text no. 1
  [Full text]  
Saito M, Nikaido Y, Matsumoto M, Ogawa M, Villanueva SYAM. The current status of diagnostic tools for leptospirosis. Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi 2017; 27:65–72.  Back to cited text no. 2
Gurumurthy K, Narasimha HB, Wyawahare M, Biswal N. Leptospirosis: a diagnostic conundrum. Trop Doct 2018; 48:306–309.  Back to cited text no. 3
Samir A, Soliman R, El-Hariri M. Leptospirosis in animals and human contacts in Egypt: broad range surveillance. Rev Soc Bras Med Trop 2015; 48:272–277.  Back to cited text no. 4


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